منابع مشابه
Primary Graft Dysfunction After Lung Transplantation.
Primary graft dysfunction is a form of acute injury after lung transplantation that is associated with significant short- and long-term morbidity and mortality. Multiple mechanisms contribute to the pathogenesis of primary graft dysfunction, including ischemia reperfusion injury, epithelial cell death, endothelial cell dysfunction, innate immune activation, oxidative stress, and release of infl...
متن کاملLong Term Impact of Primary Graft Dysfunction after Lung Transplantation
According to the International Society for Heart and Lung Transplantation (ISHLT) Registry, graft failure accounted for 24.7% of deaths within 30 days of transplantation among adult lung recipients between 1992 and 2012 [1]. Although important details distinguishing different causes of early graft failure may be missing from the Registry data, it is likely that primary graft dysfunction (PGD) i...
متن کاملLung rejection after transplantation.
With the introduction of Cyclosporine as an immunosuppressive agent, combined heart and lung transplantation (HLTx) became an effective treatment for severe pulmonary vascular disease [1] and has been extended successfully to treat end-stage lung disease [2] and cystic fibrosis [3, 4]. Single lung transplantation offers a treatment for cryptogenic fibrosing alveolitis [5]. It was initially beli...
متن کاملRejection after Lung Transplantation?
How does the body recognize the donor lung as different? Your body’s natural immune cells are able to recognize small, unique proteins called “antigens” that are present on the surface of all cells or infectious particles. These immune cells, called the T cells and the B cells, can recognize the antigens as “self” if they belong to you or “non-self” if they do not belong to you (such as those i...
متن کاملMechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation
Distinct phenotypes of chronic lung allograft dysfunction (CLAD) after lung transplantation are emerging with lymphocytic bronchiolitis (LB)/azithromycin reversible allograft dysfunction (ARAD), classical or fibrotic bronchiolitis obliterans syndrome (BOS), and restrictive allograft syndrome (RAS) proposed as separate entities. We have additionally identified lung transplant recipients with pri...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Imaging
سال: 2014
ISSN: 1936-878X
DOI: 10.1016/j.jcmg.2014.08.004